Doctors have long known that some antidepressants and other medicines can lower the amount of tamoxifen 's active form in the bloodstream .
医生很早就知道,某些抗抑郁药物可以降低他莫昔芬在血液中的活性成分浓度。
However , only 150 women in the study took such combos for more than two months , and they were compared to women taking combos for a shorter time - not to women using tamoxifen alone .
It found that using these interfering drugs - including prozac , paxil or zoloft - can virtually wipe out the benefit tamoxifen provides .
它发现,使用这些干扰药物包括百忧解、帕罗西汀以及左洛复可以消除他莫昔芬的药物作用。
The two researchers , along with a team of colleagues , took powdered paclitaxel , camptothecin , resveratrol and tamoxifen and put them in water . They then blasted each mixture with powerful sound waves for up to an hour , to break the drugs up into tiny bits .