Yet campbell says in hiv-infected children , the " unanticipated positive consequences " of ritonavir could have the added benefit of reducing persistent parasitemia caused by malaria , a leading cause of anemia in young children in many african countries .
Recurrent cases in the ritonavir group plummeted by a highly significant 59 % .
复发病例服用利托那韦组病例减少了59%,具有统计学上高度的显著性意义。
Given that ritonavir blocks cytochrome p450 , a liver enzyme that plays a key role in metabolizing drugs , the researchers wondered whether the drug might have extended lumefantrine 's preventive effects .
If ritonavir " potentiates the long tail of lumefantrine , " he says , " we certainly want to know . "
利托那韦是否“会延长苯芴醇的药效时间,”他说,“我们确实需要了解。”
When it came to first episodes , the group taking ritonavir had a 29 % reduction in malaria cases , which hinted at some effect but was not statistically significant .