Patients should be monitored during the first 4 to 8 weeks of treatment with risperidone and carbamazepine or other enzyme inducers ; dose increases or additional oral risperidone may need to be considered .
If approved by the fda for these indications , they will join the 2 antipsychotic drugs currently approved for treatment of schizophrenia and bipolar disorder in children - risperidone and aripiprazole .
These findings were supported by results from a second study ( n = 240 ) , showing that the addition of long-acting risperidone injection significantly delayed the time to relapse in patients receiving lithium or valproate therapy during 52 weeks .
Data from the first study ( n = 501 ) showed that treatment with long-acting risperidone injection significantly delayed the time to relapse of any mood episode ( depression , mania , hypomania , or mixed ) relative to placebo during 2 years .
May 27 , 2009 - the us food and drug administration ( fda ) has approved risperidone long-acting injection for use alone or with lithium or valproate in the treatment of bipolar I disorder ; and certolizumab pegol for the treatment of moderate to severely active rheumatoid arthritis .
Drug interactions with some anticonvulsants and risperidone have been noted .
我们已经注意到一些抗惊厥药物与利培酮间的药物相互作用。
Moderate effects sizes were found for quetiapine in the treatment of generalized anxiety disorder and risperidone for obsessive-compulsive disorder .
喹硫平治疗经常焦虑症和利培酮治疗强迫症被发现有适当的作用。(求指教!)
Oral risperidone , or another antipsychotic medication , should be given with the first dose of risperidone long-acting injection and continued for 3 weeks to ensure adequate therapeutic plasma concentrations .