Colorectal cancer is one of the most common malignant neoplasms , and apoptotic dysfunction plays an important role in its tumorigenesis and metastasis .
大肠癌为常见的恶性肿瘤,细胞凋亡调控失常在其发生和发展中起着重要作用。
Paradoxically , autophagy defects are associated with increased tumorigenesis , but the mechanism behind this has not been determined .
自相矛盾的是,自噬缺陷与肿瘤发生的呈正相关,但这背后的机制仍没有被明确。
Translational control gone awry : a new mechanism of tumorigenesis and novel targets of cancer treatments .
翻译控制出错作为肿瘤发生和癌症治疗新靶标的新机制。
Cancer 's sweet tooth : the janus effect of glucose metabolism in tumorigenesis .
癌症喜好甜食:肿瘤发生中葡萄糖代谢的两面效应。
Due to the continuously deepening research on aurora kinases recently , the key functions of aurora kinases in cell mitosis and tumorigenesis have been gradually revealed .
Centrosome amplification and telomere shortening , which are commonly detected in human cancers , have been implicated in the induction of chromosome instability in tumorigenesis .
端粒缩短。这两大癌细胞的特征促使肿瘤发生过程中染色体不稳定。
Geminin is a multifunctional protein which localizes in nucleus , it has complicated structural and functional domains . Geminin plays very important roles in cell proliferation , embryonic development , tumorigenesis and so on .