In the load brain samples we identified a notably age-specific epigenetic drift supporting a potential role of epigenetic effects in the development of the disease .
Scientists have even identified specific epigenetic patterns on the genes of people who smoke .
科学家们甚至已鉴定了吸烟人群基因上的特殊表观模式。
Most researchers had thought that such epigenetic changes only occurred while a person was developing in the womb .
大部分研究者认为这些外遗传的变化只会出现在一个人孕育在子宫时。
In parallel , he wants to mathematically model the epigenetic effects and incorporate them into population genetics models , to understand dynamic inheritance patterns that cannot be explained by purely mendelian genetics .